BDB610786
α-Synuclein Mouse, Unlabeled, Clone: 42, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB610786-Each-of-1 | In Stock | ₹ 25,587.50 |
BDB610786 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,587.50
GST (18%): ₹ 4,605.75
Total Price: ₹ 30,193.25
Antigen
α-Synuclein
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Rat Synuclein-1 aa. 15-123
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Human, Mouse, Rat
Isotype
IgG1
Applications
Western Blot
Clone
42
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Related Products
Description
- Synuclein cDNA was isolated from Torpedo californica and found to encode a 143 amino acid neuron-specific protein
- In addition, a rat brain cDNA library yielded several clones that encode different proteins with homology to Torpedo Synuclein
- A 140 amino acid protein in rat is referred to as Synuclein-1
- In situ hybridization shows synuclein mRNAs in discrete areas of rat brain, notably the hippocampus
- In humans, two synuclein proteins of 140 and 134 amino acids were sequenced that exhibit a high degree of homology with each other (61% identity) and with previously described Synuclein proteins
- The 140 amino acid protein (α-Synuclein) is the human homologue of rat Synuclein-1 and is identical to the non-amyloid-β component precursor (NACP), a presynaptic protein involved in amyloidogenesis in Alzheimer's disease (AD)
- The 134 amino acid protein (β-Synuclein) is the human homologue of bovine phosphoneuroprotein
- These proteins are expressed in brain, primarily in presynaptic nerve terminals
- Although the exact function of the Synucleins has not been determined, they have been linked to the prominent neurodegenerative disorders AD and Parkinson's disease
- Immunofluorescence, Immunoprecipitation, Western Blotting