BDB612776
CD64 Mouse anti-Human, Brilliant Ultraviolet 737, Clone: 10.1, BD Horizon™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB612776-Each-of-1 | In Stock | ₹ 42,008.00 |
BDB612776 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,008.00
GST (18%): ₹ 7,561.44
Total Price: ₹ 49,569.44
Antigen
CD64
Classification
Monoclonal
Conjugate
Brilliant Ultraviolet 737
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
10.1
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses
- CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells
- CD64 associates with a signaling FcRγhomodimer to form the functional high affinity FcγRI complex
- CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation
- Due to spectral differences between labeled cells and beads, using BD™ CompBeads can result in incorrect spillover values when used with BD Horizon BUV737 reagents
- Therefore, the use of BD CompBeads or BD CompBeads Plus to determine spillover values for these reagents is not recommended
- Different BUV737 reagents (e.g., CD4 vs
- CD45) can have slightly different fluorescence spillover therefore, it may also be necessary to use clone specific compensation controls when using these reagents.