BDB641057
CD8b Mouse anti-Human, PE, Clone: 2ST8.5H7, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB641057-Each-of-1 | In Stock | ₹ 29,904.00 |
BDB641057 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,904.00
GST (18%): ₹ 5,382.72
Total Price: ₹ 35,286.72
Antigen
CD8b
Classification
Monoclonal
Concentration
6μg/mL
Formulation
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen
CD8
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Applications
Flow Cytometry
Clone
2ST8.5H7
Conjugate
PE
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Related Products
Description
- The CD8β antibody, clone 2ST8.5H7, is derived from the hybridization NS-1 mouse tumor cells with splenocytes from Balb/c mice immunized with CD8 + suppressor T-cell clone termed 20a6
- The CD8β antibody recognizes an epitope formed by the combination of CD8 alpha and beta chains
- The majority of peripheral blood CD8 + T lymphocytes expresses an α/β heterodimer (32, 30 kilodaltons (kDa)), while CD8 + CD16 + natural killer (NK) lymphocytes and CD8 + T-cell receptor (TCR)-γ/δ NK cells
- The CD8 antigenic determinant binds to class I major histocompatibility (MHC) molecules, resulting in increased adhesion between the CD8 + T lymphocytes and target cells
- Binding of the CD8 antigen to class I MHC molecules enhances the activation of resting T lymphocytes
- The CD8 antigen is coupled to a protein tyrosine kinase, p56 lck
- The CD8:p56 lck complex can play a role in T-lymphocyte activation through mediation of the interactions between the CD8 antigen and the CD3/TCR complex.