BDB740094

CD54 Mouse anti-Human, Brilliant Violet 421, Clone: LB-2, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740094-Each-of-1 In Stock ₹ 49,528.50

BDB740094 - Each of 1

₹ 49,528.50

In Stock

Quantity

1

Base Price: ₹ 49,528.50

GST (18%): ₹ 8,915.13

Total Price: ₹ 58,443.63

Antigen

CD54

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Human ICAM-1, HICAM-1; BB2; P3.58

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

LB-2

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Major histocompatibility Class II antigen negative variant of human B-lymphoblastoid cell line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The LB-2 monoclonal antibody specifically binds to CD54 which is also known as Intercellular adhesion molecule-1 (ICAM-1)
  • CD54 is an 85-110 kDa type I transmembrane glycoprotein that belongs to the immunoglobulin supergene family
  • A soluble form of CD54 can also be found in biological fluids
  • CD54 is expressed on endothelial cells and both resting (weak) and activated (moderate) T and B lymphocytes and monocytes
  • CD54 is expressed on human myeloma cells, Burkitt's lymphoma cells, erythroleukemia cells, and B-lymphoblastoid cells
  • CD54 is a ligand for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) and can act as a receptor for Rhinoviruses
  • The CD54 adhesion molecule plays roles in inflammatory and immune responses and neoplasia
  • The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
  • BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.