BDB740143

CD90/CD90.1 Mouse anti-Mouse, Brilliant Violet 510, Clone: OX-7 (also known as OX7), BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740143-Each-of-1 In Stock ₹ 35,422.00

BDB740143 - Each of 1

₹ 35,422.00

In Stock

Quantity

1

Base Price: ₹ 35,422.00

GST (18%): ₹ 6,375.96

Total Price: ₹ 41,797.96

Antigen

CD90/CD90.1

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Rat Thy-1; Mouse Thy-1.1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

OX-7 (also known as OX7)

Conjugate

Brilliant Violet 510

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Rat Thymocyte Thy-1 Antigen

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • CD90 (Thy-1) is a GPI-anchored membrane glycoprotein of the Ig superfamily which is involved in signal transduction
  • The OX-7 monoclonal antibody specifically binds to rat CD90 reported to be expressed by hematopoietic stem cells, early myeloid and erythroid cells, immature B lymphocytes in the bone marrow and peripheral lymphoid organs, thymocytes, recent thymic emigrants (a subset of CD45RC- peripheral T lymphocytes), neurons, glomerular mesangial cells, endothelium at inflammatory sites, mast cells, and dendritic cells
  • Rat dendritic epidermal T cells (DEC) have been reported to be CD90 (Thy-1) negative, unlike those of the mouse
  • The OX-7 clone has been reported to crossreact with the mouse CD90.1 (Thy-1.1) alloantigen of the AKR/J and PL strains, but not CD90.2 (Thy-1.2) found on many mouse strains
  • In the mouse, CD90 is found on thymocytes, most peripheral T lymphocytes, some intraepithelial T lymphocytes (IEL, DEC), hematopoietic stem cells, and neurons, but not B lymphocytes
  • In addition, there is evidence that CD90 mediates adhesion of mouse thymocytes to mouse thymic stroma
  • The OX-7 clone has also been reported to crossreact with rabbit and guinea pig thymus, brain, and intestine.