BDB740214

CD11a Rat anti-Mouse, BUV395, Clone: 2D7, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740214-Each-of-1 In Stock ₹ 35,600.00

BDB740214 - Each of 1

₹ 35,600.00

In Stock

Quantity

1

Base Price: ₹ 35,600.00

GST (18%): ₹ 6,408.00

Total Price: ₹ 42,008.00

Antigen

CD11a

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Itgal; Integrin alpha-L; Integrin αL; ITAL; LFA-1A; LFA-1α; Ly-15

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

2D7

Conjugate

Brilliant Ultraviolet 395

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Not Reported

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 2D7 monoclonal antibody specifically binds to the 180-kDa α L chain of LFA-1 (CD11a/CD18, α L β 2 integrin), a heterodimeric surface glycoprotein expressed on almost all leukocytes
  • CD8a+CD8b- intestinal intraepithelial T lymphocytes, which are believed to be thymus independent, do not express CD11a
  • LFA-1 mediates a variety of heterotypic and homotypic intracellular adhesions through interaction with ICAM-1 (CD54) and ICAM-2 (CD102), including participation in the immunological synapses between CD8+ T lymphocytes and antigen-presenting cells
  • mAb 2D7 has been reported to block an in vitro allogeneic mixed-leukocyte reaction
  • The 2D7 and M17/4 (Cat
  • No
  • 553337, for the NA/LE™ format) antibodies are reported to recognize different epitopes of the CD11a molecule.