BDB740222
CD54 Hamster anti-Mouse, BUV395, Clone: 3E2, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB740222-Each-of-1 | In Stock | ₹ 35,600.00 |
BDB740222 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,600.00
GST (18%): ₹ 6,408.00
Total Price: ₹ 42,008.00
Antigen
CD54
Classification
Monoclonal
Concentration
0.2mg/mL
Description
ICAM-1; Icam1; Intercellular adhesion molecule 1; Ly-47; MALA-2; MyD10
Host Species
Hamster
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
3.00E+02
Conjugate
Brilliant Ultraviolet 395
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Not reported
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The 3E2 monoclonal antibody specifically binds to CD54 (ICAM-1), a 95-kDa member of the Ig superfamily found on lymphocytes, vascular endothelium, high endothelial venules, epithelial cells, macrophages, and dendritic cells
- ICAM-1 is a ligand for LFA1 (CD11a/CD18) and Mac-1 (CD11b/CD18)
- Its expression is upregulated upon stimulation by inflammatory mediators such as cytokines and LPS
- Studies with mouse Icam1 -transfected antigen-presenting cells, with CD54-blocking antibodies, and in CD54-deficient mice indicate that CD54 participates in inflammatory reactions and antigen-specific immune responses
- In addition, there is evidence that CD54 is a receptor involved in MHC-non-restricted responses to weakly immunogenic tumor cells
- The 3E2 antibody has been reported to block in vitro and in vivo intracellular adhesion events involved in immune responses
- The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
- This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
- With an Ex Max at 348nm and an Em Max at 395nm, BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.