CD7 Mouse anti-Human, Brilliant Violet 605, Clone: M-T701, BD Optibuild™

Description

• The M-T701 monoclonal antibody specifically binds to CD7
• CD7 is a 40 kDa type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily
• The CD7 antigen is also known as Leu-9, TP41, Tp40, GP40, and T-cell leukemia antigen
• It is expressed on thymocytes, T cells, pre-B cells, and NK cells
• CD7 is present in reduced density on monocytic cells and cell lines
• Functional studies demonstrate that crosslinking of the CD7 can induce transmembrane calcium flux in T cells
• This antibody is conjugated to BD Horizon™ BV605 which is part of the BD Horizon Brilliant™ Violet family of dyes
• With an Ex Max of 407-nm and Em Max of 602-nm, BD Horizon BV605 can be excited by a violet laser and detected with a standard 610/20-nm filter set
• BD Horizon BV605 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an Em max at 605-nm
• Due to the excitation of the acceptor dye by the green (532 nm) and yellow-green (561 nm) lasers, there will be significant spillover into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers
• BD Horizon BV605 conjugates are very bright, often exhibiting brightness equivalent to PE conjugates and can be used as a third color off of the violet laser.