BDB740473

CD61 Hamster anti-Mouse, Brilliant Violet 650, Clone: 2C9.G2, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740473-Each-of-1 In Stock ₹ 35,422.00

BDB740473 - Each of 1

₹ 35,422.00

In Stock

Quantity

1

Base Price: ₹ 35,422.00

GST (18%): ₹ 6,375.96

Total Price: ₹ 41,797.96

Antigen

CD61

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Itgb3; Integrin beta-3; INGRB3; Platelet glycoprotein IIIa; GP3A; GPIIIa

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

2C9.G2

Conjugate

Brilliant Violet 650

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse T-cell Hybridoma 2B4 Vitronectin Receptor

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 2C9.G2 monoclonal antibody specifically binds to the integrin β 3 chain (CD61), which associates with the integrin α v chain (CD51) to form the vitronectin receptor and with the α IIb chain (CD41) to form the gpIIb/IIIa complex
  • Both receptors mediate adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor
  • Leukocyte-endothelial adhesion is also mediated by the binding of α v β 3 integrin or vitronectin receptor to CD31 (PECAM-1)
  • In addition, interaction of the α v β The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 650-nm
  • BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20-nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination.