BDB740493
LPAM-1 Rat anti-Mouse, Brilliant Violet 650, Clone: DATK32, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB740493-Each-of-1 | In Stock | ₹ 35,600.00 |
BDB740493 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,600.00
GST (18%): ₹ 6,408.00
Total Price: ₹ 42,008.00
Antigen
LPAM-1
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Itga4Itgb7; α4β7 Integrin; alpha 4 beta 7 integrin; CD49dβ7
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
DATK32
Conjugate
Brilliant Violet 650
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
AKR/Cum mouse T lymphoma line TK1
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The DATK32 monoclonal antibody specifically binds to an epitope specific for the α 4β 7 integrin heterodimer
- α 4β 7 (LPAM-1) is expressed on most mature lymphocytes and on small subsets of thymic and bone marrow cells
- It interacts with several ligands, including VCAM-1 (CD106), fibronectin, and MAdCAM-1
- DATK32 antibody induces α 4β 7-dependent lymphocyte aggregation, but it inhibits other α The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 650-nm
- BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20-nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- However, the spillover can be corrected through compensation as with any other dye combination.