BDB740511

CD126 Rat anti-Mouse, Brilliant Violet 650, Clone: D7715A7, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740511-Each-of-1 In Stock ₹ 35,422.00

BDB740511 - Each of 1

₹ 35,422.00

In Stock

Quantity

1

Base Price: ₹ 35,422.00

GST (18%): ₹ 6,375.96

Total Price: ₹ 41,797.96

Antigen

CD126

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Il6ra; IL-6 Receptor α chain; IL-6RA; IL-6R alpha

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

D7715A7

Conjugate

Brilliant Violet 650

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

OKT4 hybridoma cells

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The D7715A7 monoclonal antibody specifically binds to the mouse IL-6 receptor, which is also known as, CD126
  • The immunogen used to generate the D7715A7 hybridoma was OKT4 hybridoma cells
  • The D7715A7 hybridoma was selected based on its capacity to produce antibody that inhibited IL-6 binding to 2F4 cells (mouse B-cell hybridoma expressing high levels of IL-6 receptors)
  • The binding of purified D7715A7 to B9 cells (mouse B-cell hybridoma expressing high levels of IL-6 receptors) is inhibited by recombinant mouse IL-6
  • This antibody has been reported to inhibit the in vitro and in vivo growth of the IL-6-dependent plasmacytoma line, T1033C2.