BDB740942

CD153 Rat anti-Mouse, Brilliant Violet 786, Clone: RM153, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740942-Each-of-1 In Stock ₹ 35,600.00

BDB740942 - Each of 1

₹ 35,600.00

In Stock

Quantity

1

Base Price: ₹ 35,600.00

GST (18%): ₹ 6,408.00

Total Price: ₹ 42,008.00

Antigen

CD153

Classification

Monoclonal

Concentration

0.2mg/mL

Description

CD30 Ligand; Cd30l; CD30LG; Tnfsf8

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

RM153

Conjugate

Brilliant Violet 786

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

CHO cells transfected with mouse CD153 gene (Tnfsf8)

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The RM153 monoclonal antibody specifically recognizes a 40-kDa type-II membrane glycoprotein, CD30 ligand (CD30L or CD153), which belongs to the NGF/TNF superfamily
  • In the presence of cytokines, CD153 stimulates B-cell proliferation, antigen-specific antibody production, and polyclonal immunoglobulin secretion
  • In addition, it costimulates the proliferation of activated T cells
  • This molecule is expressed on activated T cells, predominantly CD4+, on activated EL4 cells, and on activated Th1 and Th2 cells
  • The RM153 mAb inhibits the binding of CD153 to CD30
  • The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm
  • BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).