BDB741025

CD125 Rat anti-Mouse, Brilliant Violet 786, Clone: T21, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB741025-Each-of-1 In Stock ₹ 35,422.00

BDB741025 - Each of 1

₹ 35,422.00

In Stock

Quantity

1

Base Price: ₹ 35,422.00

GST (18%): ₹ 6,375.96

Total Price: ₹ 41,797.96

Antigen

CD125

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Il5r; Il5ra; IL-5RA; IL-5Rα; IL-5R-alpha; IL-5R subunit alpha

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 λ

Applications

Flow Cytometry

Clone

T21

Conjugate

Brilliant Violet 786

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse T88-M Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The T21 monoclonal antibody specifically binds to CD125 which is also known as the alpha subunit of the IL-5 Receptor (IL5RA/IL-5R α )
  • CD125 is a type I transmembrane protein that belongs to the hemopoietin receptor and Ig gene superfamilies
  • It is expressed on B cells and eosinophils
  • CD125 associates with the Common β chain ( β c/Bc) subunit, also known as CD131, to form the functional IL-5 Receptor complex
  • Mouse IL-5 belongs to the hematopoietic growth factor family of cytokines and promotes the growth and differentiation of B cells and eosinophils
  • Upon binding, the T21 antibody blocks IL-5 binding to its receptor and can inhibit IL-5 induced B-cell proliferation and antibody production.