BDB741039

CD276 Rat anti-Mouse, Brilliant Violet 786, Clone: MIH32, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB741039-Each-of-1 In Stock ₹ 35,600.00

BDB741039 - Each of 1

₹ 35,600.00

In Stock

Quantity

1

Base Price: ₹ 35,600.00

GST (18%): ₹ 6,408.00

Total Price: ₹ 42,008.00

Antigen

CD276

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Cd276; B7-H3; B7 homolog 3; B7h3; B7RP-2; Costimulatory molecule

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

MIH32

Conjugate

Brilliant Violet 786

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse B7-H3 Transfected Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The MIH32 monoclonal antibody specifically binds to CD276, also known as B7-H3 (B7 homolog 3)
  • CD276 is a type I transmembrane glycoprotein and member of the B7-family of regulatory proteins
  • The expression of B7-H3 can be induced on T cells, natural killer (NK) cells and antigen presenting cells
  • B7-H3 is up-regulated during the differentiation of monocytes into dendritic cells or during the interaction between dendritic cells and regulatory T cells
  • In addition, B7-H3 is found to be expressed on fibroblasts, fibroblast-like synoviocytes and epithelial cells
  • CD276 (B7-H3) can function as a positive or a negative regulator of T responses
  • The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm
  • BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).