CB1001500UG
MilliporeSigma™ anti-GAPDH Clone: 6C5,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | CB1001500UG-Each-of-1 | In Stock | ₹ 50,445.20 |
CB1001500UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,445.20
GST (18%): ₹ 9,080.136
Total Price: ₹ 59,525.336
Antigen
GAPDH
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Canine, Chicken, Fish, Frog, Human, Mouse, Porcine, Rabbit, Rat
Form
Purified
Applications
ELISA, Immunoblot, Immunoblot, Immunocytochemistry
Clone
6C5
Formulation
In PBS, pH 7.4.
Immunogen
purified, rabbit muscle
Regulatory Status
RUO
Test Specificity
Recognizes the ∽146kDa GAPDH protein under non-reducing conditions and the ∽36kDa monomeric subunits under reducing conditions.
Content And Storage
2°C to 8°C
Isotype
IgG1
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Description
- Specifically detects GAPDH Clone: 6C5 in Canine, Chicken, Fish, Frog, Human, Mouse, Porcine, Rabbit, Rat samples, and it is validated for ELISA, Immunocytochemistry, Immuno Blotting Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is one of the key enzymes involved in glycolysis
- GAPDH is comprised of four ∽36kDa subunits with a total molecular weight of ∽146kDa
- Besides functioning as a glycolytic enzyme in cytoplasm, mammalian GAPDH is also involved in a great number of intracellular processes such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication and DNA repair
- Recently, findings have been made concerning the role of GAPDH in differentpathologies including prostate cancer progression, programmed neuronal cell death, and age-related neuronal diseases such as Alzheimer’s Disease and Huntington’s Disease
- While GAPDH is constitutively expressed in almost all tissues at high levels, there are some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types.