IL-4 Monoclonal Antibody (24G2), Biotin, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ENMM450DB-Each-of-1 | In Stock | ₹ 46,235.50 |
ENMM450DB - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,235.50
GST (18%): ₹ 8,322.39
Total Price: ₹ 54,557.89
Antigen
IL-4
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 4% BSA and proprietary Preservative
Gene Accession No.
P07750
Gene Symbols
Il4
Immunogen
Recombinant mouse IL-4
Quantity
250 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Western Blot
Clone
24G2
Conjugate
Biotin
Gene
Il4
Gene Alias
B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
Host Species
Rat
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
16189
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- MM450DB targets IL-4 in ELISA, and WB applications and shows reactivity with mouse samples
- The MM450DB immunogen is recombinant mouse IL-4
- MM450DB detects IL-4 which has a predicted molecular weight of approximately 14 kDa
- The MM450DB mouse IL4 antibody (biotinylated conjugate of clone 24G2) has successfully been paired as the detection antibody in a sandwich ELISA with capture antibody MM450C (clone 1D11)
- Typical dilutions for sandwich ELISA include 1 μg/mL for coating and 0.125 - 0.25 μg/mL for detection
- Biotinylated antibody MM450DB (clone 24G2) and antibody MM450C (clone 1D11) have successfully been used in combination with recombinant mouse IL4 protein SMIL4 in ELISA applications
- This antibody is produced by injecting Rat IgG secreting hybridoma cells into the peritoneum of mice
- The resulting ascites is collected from the mice and the antibody is purified
- Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor
- IL-4 has been found to have the broadest range of actions
- The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13
- STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4
- The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q
- In particular, IL-4 is located in close proximity to IL13 on the chromosome
- Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome
- IL-4 delta 2 is a known splice variant of IL-4.