Plasma Kallikrein Recombinant Rabbit Monoclonal Antibody (9F6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549855-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA549855 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
Plasma Kallikrein
Classification
Recombinant Monoclonal
Concentration
0.33 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P03952
Gene Symbols
Klkb1
Immunogen
A synthesized peptide derived from human KLKB1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin)
Clone
9F6
Conjugate
Unconjugated
Gene
Klkb1
Gene Alias
antigen, prostate specific, APS, EC 3.4.21.34, Fletcher factor, Kal3, Kal-3, kallikrein, kallikrein 3, plasma, kallikrein B plasma, kallikrein B, plasma (Fletcher factor) 1, kallikrein B, plasma 1, kallikrein B1, Kalp1, KALP15, kininogenin, Klk3, KLKB1, Pk, PKK, PKKD, plasma kallikrein, Plasma kallikrein heavy chain, Plasma kallikrein light chain, Plasma prekallikrein, PPK, prekallikrein, PSA
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3818
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation
- It is synthesized in the liver and secreted into the blood as a single polypeptide chain
- Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond
- Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond
- The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids
- Each repeat harbors a novel structure called the apple domain
- The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein
- The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases
- Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.