FEMA549923

SMN1 Recombinant Rabbit Monoclonal Antibody (8B10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549923-Each-of-1 In Stock ₹ 37,202.00

FEMA549923 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

SMN1

Classification

Recombinant Monoclonal

Concentration

1.5 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q16637

Gene Symbols

SMN1

Immunogen

A synthesized peptide derived from human SMN1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

8B10

Conjugate

Unconjugated

Gene

SMN1

Gene Alias

AI849087, BCD541, component of gems 1, Gemin1, Gemin-1, SMA, SMA@, SMA1, SMA2, SMA3, SMA4, Smn, SMN1, SMN2, SMNC, SMNT, survival motor neuron 1, survival motor neuron 1 protein, survival motor neuron protein, survival of motor neuron 1, telomeric, survival of motor neuron protein, T-BCD541, TDRD16A, tudor domain containing 16A

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6606

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13
  • This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions
  • The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region
  • The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein
  • The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome
  • Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.