FEMA550167

MICA Recombinant Rabbit Monoclonal Antibody (9F1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550167-Each-of-1 In Stock ₹ 37,202.00

FEMA550167 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

MICA

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q29983

Gene Symbols

MICA

Immunogen

A synthesized peptide derived from Human MICA

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

9F1

Conjugate

Unconjugated

Gene

MICA

Gene Alias

DAMA-345G11.2, HLA class I antigen, MHC class I chain-related protein A, MHC class I polypeptide-related sequence A, MHC class I related sequence A, MICA, MIC-A, PERB11.1, stress inducible class I homolog, truncated MHC class I polypeptide-related sequence A

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100507436

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Major histocompatibility complex (MHC) class I proteins are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells
  • A related family, termed the MHC class I chain-related (MIC) proteins are recognized by NKG2D, a receptor on NK and T cells, and promote anti-tumor activity
  • MICA, a member of the MIC family, is widely expressed on many tumors, and it is the MICA/NKG2D interaction that is thought to stimulate the anti-tumor reactivity by T lymphocytes
  • Both MICA and MICB mRNA are widely expressed in normal tissues, with MICA being present in virtually every tissue except the nervous system, suggesting that MIC protein expression may only be one component of the anti-tumor activity of the immune system.