FEMA550448

MLK4 Recombinant Rabbit Monoclonal Antibody (HL2234), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550448-Each-of-1 In Stock ₹ 41,385.00

FEMA550448 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

MLK4

Classification

Recombinant Monoclonal

Concentration

2 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q5TCX8

Gene Symbols

MAP3K21

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human MLK4. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

HL2234

Conjugate

Unconjugated

Gene

MAP3K21

Gene Alias

BC021891, cDNA sequence BC021891, dJ862P8.3, Kiaa1804, MAP3K21, Mitogen-activated protein kinase kinase kinase 21, Mitogen-activated protein kinase kinase kinase MLK4, mixed lineage kinase 4, mKIAA1804, MLK4, RGD1306091, similar to Mixed lineage kinase 4

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

84451

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • MLK4 or mixed lineage kinase 4 belongs to the superfamily of MAP kinase kinases (MAP3K1) which contain both ser/thr and tyr kinases activity in their catalytic domains
  • The structure of this kinase family incorporates an N-terminal Src homology (SH3) domain, followed by the kinase domain, a leucine zipper region, and a CDC42 /RAC -interactive binding (CRIB) motif, but divergent C-terminal regions
  • MLK4 is highly expressed in kidney and pancreas
  • MLK4 is a negative regulator of TLR4 and does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.