FEMA550457

SDHB Recombinant Rabbit Monoclonal Antibody (HL2251), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550457-Each-of-1 In Stock ₹ 41,385.00

FEMA550457 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

SDHB

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P21912, P21913, Q9CQA3

Gene Symbols

Sdhb

Immunogen

Recombinant fragment of human SDHB.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

HL2251

Conjugate

Unconjugated

Gene

Sdhb

Gene Alias

0710008N11Rik, CWS2, fj46d06, FLJ92337, I79_022285, Ip, iron-sulfur subunit, iron-sulfur subunit of complex II, OTTHUMP00000044624, PGL4, SDH, SDH1, SDH2, Sdhb, SDHB protein, SDHB, sdhB, SDHIP, succinate dehydrogenase [ubiquinone] iron-sulfur subunit, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, succinate dehydrogenase complex iron sulfur subunit B, succinate dehydrogenase complex subunit B, succinate dehydrogenase complex subunit B, iron sulfur (Ip), succinate dehydrogenase complex, subunit B, iron sulfur (Ip), succinate dehydrogenase Ip subunit, succinate dehydrogenase iron-protein subunit, wu:fj46d06

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

298596, 6390, 67680

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ
  • The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane
  • The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme
  • Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.