FEMA550484

ARID1A Recombinant Rabbit Monoclonal Antibody (HL2304), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550484-Each-of-1 In Stock ₹ 41,385.00

FEMA550484 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

ARID1A

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

A2BH40, O14497

Gene Symbols

ARID1A

Immunogen

Recombinant fragment of human ARID1A.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

HL2304

Conjugate

Unconjugated

Gene

ARID1A

Gene Alias

1110030E03Rik, ARID domain-containing protein 1A, ARID1A, AT rich interactive domain 1A (Swi1 like), AT rich interactive domain 1A (SWI-like), AT-rich interaction domain 1A, AT-rich interactive domain-containing protein 1A, B120, BAF250, Baf250a, BM029, brain protein 120, BRG1-associated factor 250, BRG1-associated factor 250a, C1orf4, chromatin remodeling factor p250, CSS2, ELD, h BM029, hELD, hOSA1, MRD14, Osa homolog 1, Osa1, OSA1 nuclear protein, P270, Smarcf1, SWI/SNF complex protein p270, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1, SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1, Swi1 like, SWI-like protein, SWI-SNF complex protein p270

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

297867, 8289, 93760

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Description This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes
  • The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin
  • It possesses at least two conserved domains that could be important for its function
  • First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus
  • Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation
  • It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions
  • Two transcript variants encoding different isoforms have been found for this gene.