TNF alpha Recombinant Rabbit Monoclonal Antibody (HL2363), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550505-Each-of-1 | In Stock | ₹ 41,385.00 |
FEMA550505 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
TNF alpha
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P01375
Gene Symbols
Tnf
Immunogen
Full length human TNF alpha recombinant protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA
Clone
HL2363
Conjugate
Unconjugated
Gene
Tnf
Gene Alias
APC1 protein, Cachectin, C-domain 1, C-domain 2, cTNF, DADB-70P7.1, DIF, ICD1, ICD2, Intracellular domain 1, Intracellular domain 2, N-terminal fragment, NTF, RATTNF, Tnf, TNF alpha, TNF superfamily, TNF a, TNF, macrophage-derived, TNF, monocyte-derived, TNFA, TNF-a, TNFalpha, TNF-alpha, Tnfsf1a, TNFSF2, TNFa, TNLG1F, Tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor alpha (cachetin), tumor necrosis factor alpha precursor, tumor necrosis factor ligand 1F, tumor necrosis factor ligand superfamily member 2, Tumor necrosis factor, membrane form, Tumor necrosis factor, soluble form, tumor necrosis factor-alpha, tumor necrosis factor-alpha precursor, tumor-necrosis factor, tumour necrosis factor
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
7124
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- This product can be used in Sandwich ELISA to detect TNF alpha using MA5-50505 as a capture antibody and MA5-50504 TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
- This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
- TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
- TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
- Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
- Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
- TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
- This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.