CCR4 Recombinant Rabbit Monoclonal Antibody (HL2481), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550549-Each-of-1 | In Stock | ₹ 41,385.00 |
FEMA550549 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
CCR4
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P51679, P51680
Gene Symbols
Ccr4
Immunogen
Synthetic peptide of human CCR4.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
HL2481
Conjugate
Unconjugated
Gene
Ccr4
Gene Alias
C-C chemokine receptor 4, C-C chemokine receptor type 4, C-C CKR-4, C-C motif chemokine receptor 4, CC-CKR-4, Ccr4, CCR-4, CD194, chemokine (C-C motif) receptor 4, chemokine (C-C) receptor 4, CHEMR1, ChemR13, CKR4, Cmkbr4, fusin, HGCN:14099, K5-5, LESTR, leukocyte-expressed seven-transmembrane-domain receptor, MGC88293, Sdf1r
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1233, 12773, 171054
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- CCR4 is a chemokine receptor and is preferentially expressed on type 2 helper T (Th2-type) cells
- In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement
- Moreover, activated Th1 cells up-regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine
- Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors
- Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis
- Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines.