FEMA550803
Menin Recombinant Rabbit Monoclonal Antibody (JE30-97), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550803-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550803 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
Menin
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O00255
Gene Symbols
MEN1
Immunogen
Synthetic peptide within Human Menin aa 566-615/615.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
JE30-97
Conjugate
Unconjugated
Gene
MEN1
Gene Alias
AW045611, MEAI, MEN1, Menin, menin 1, multiple endocrine neoplasia 1, multiple endocrine neoplasia I, SCG2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4221
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: 293 cell lysate, PC-3M cell lysate, Jurkat cell lysate, human lung cancer tissue, human testis tissue
- Predicted band size: 68 kDa Subcellular Location: Nucleus
- Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells
- One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+)
- Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization
- Maxi K+ dual activation is possible because of its structure
- The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain
- In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry
- The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open.