RIP3 Monoclonal Antibody (C1), Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550918-Each-of-1 | In Stock | ₹ 16,269.20 |
FEMA550918 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,269.20
GST (18%): ₹ 2,928.456
Total Price: ₹ 19,197.656
Antigen
RIP3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.
Q9Y572, Q9Z2P5
Gene Symbols
RIPK3
Immunogen
Recombinant Rat RIPK3 protein, Val50-Pro272 (Accession #Q9Z2P5)
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
C1
Conjugate
Unconjugated
Gene
RIPK3
Gene Alias
2610528K09Rik, AW107945, Hcyp2, Homocysteine respondent protein HCYP2, mRIP3, receptor interacting protein 3, receptor interacting serine/threonine kinase 3, receptor-interacting protein 3, receptor-interacting serine/threonine-protein kinase 3, receptor-interacting serine-threonine kinase 3, Rip3, RIP-3, Ripk3, RIP-like protein kinase 3
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
11035, 246240
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG2b κ
Related Products
Description
- RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, which contains a C-terminal domain unique from other RIP family members
- RIPK3 is predominantly localized to the cytoplasm, and specifically, are colocalized in the mitochondrion which can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals
- RIPK3 is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor and caspase-8 prevents RIPK3-dependent necrosis without inducing apoptosis by functioning in a proteolytically active complex with CFLAR and that this complex is required for the protective function.