S100A12 Monoclonal Antibody (C7), Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA551112-Each-of-1 | In Stock | ₹ 16,269.20 |
FEMA551112 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,269.20
GST (18%): ₹ 2,928.456
Total Price: ₹ 19,197.656
Antigen
S100A12
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.
P80511
Gene Symbols
S100A12
Immunogen
Recombinant Human S100A12 protein, Met1-Glu92 (Accession #P80511)
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
C7
Conjugate
Unconjugated
Gene
S100A12
Gene Alias
CAAF1, CAGC, Calcitermin, calcium-binding protein in amniotic fluid 1, calgranulin C, calgranulin-C, CGRP, EN RAGE, ENRAGE, EN-RAGE, Extracellular newly identified RAGE-binding protein, migration inhibitory factor-related protein 6, MRP6, MRP-6, Neutrophil S100 protein, p6, Protein S100 A12, protein S100-A12, S100 calcium binding protein A12, S100 calcium-binding protein A12, S100 calcium-binding protein A12 (calgranulin C), S100A12
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
6283
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1 κ
Related Products
Description
- S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs
- S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation
- S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities
- S100A12 is also a ligand for RAGE
- Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation
- Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE
- S100A12 has also been shown to have anti-microbial properties.