FEMA551120

PLS3 Monoclonal Antibody (C4), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA551120-Each-of-1 In Stock ₹ 16,269.20

FEMA551120 - Each of 1

₹ 16,269.20

In Stock

Quantity

1

Base Price: ₹ 16,269.20

GST (18%): ₹ 2,928.456

Total Price: ₹ 19,197.656

Antigen

PLS3

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

P13797, Q63598

Gene Symbols

PLS3

Immunogen

Recombinant Human PLS3 protein, Ala379-Val630 (Accession #P13797)

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Porcine, Rat

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

C4

Conjugate

Unconjugated

Gene

PLS3

Gene Alias

AI115446, AL024105, BMND18, LOW QUALITY PROTEIN: plastin-3, MGC128570 protein, plastin 3, plastin 3 (T isoform), plastin 3 (T-isoform), plastin 3, T, plastin-3, PLS3, T fimbrin, T plastin, T-fimbrin, T-plastin

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

100158187, 5358, 81748

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

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Description

  • Phospholipid scramblases (PLS) translocate phospholipids bidirectionally between inner and outer leaflets of the plasma membrane and are implicated in apoptosis (1,2)
  • Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis
  • PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3
  • Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.