MPZ Monoclonal Antibody (C13), Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA551125-Each-of-1 | In Stock | ₹ 33,553.00 |
FEMA551125 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,553.00
GST (18%): ₹ 6,039.54
Total Price: ₹ 39,592.54
Antigen
MPZ
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.
P06907, P25189, P27573
Gene Symbols
MPZ
Immunogen
Recombinant Human MPZ protein, Ile30-Lys248 (Accession #P25189)
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Porcine, Rat
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
C13
Conjugate
Unconjugated
Gene
MPZ
Gene Alias
Charcot-Marie-Tooth neuropathy 1B, CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, MPZ, Myelin peripheral protein, myelin protein P0, Myelin protein zero, myelin protein zero (Charcot-Marie-Tooth neuropathy 1B), P0, P-zero
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
100153273, 17528, 24564, 4359
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG3 κ
Related Products
Description
- Zero, also known as myelin protein zero (MPZ) is a Type 1 integral membrane glycoprotein that mediates adhesion of spiraling wraps of the myelin sheath in order to ensure stable synaptic transmission
- Zero protein encompasses approximately 50% of total protein in the sheath scaffolding in contribution to structural integrity of peripheral myelin
- Zero guides the compact myelin wrapping process through glycine zipper packing interface-dependent dimer and tetramer formation
- Mutations (e.g
- G134R) can abrogate multimer formation, cause demyelinating neuropathies, and are known to contribute to conditions that include Charcot-Marie-Tooth disease
- Zero cytoplasmic domain undergoes serine and tyrosine phosphorylation, which appears to be prevalent during peak nerve myelination
- Zero transcript is moderate in brain, abundant in thymus and most abundant in white matter of the CNS.