COMT Monoclonal Antibody (C4), Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA551130-Each-of-1 | In Stock | ₹ 16,269.20 |
FEMA551130 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,269.20
GST (18%): ₹ 2,928.456
Total Price: ₹ 19,197.656
Antigen
COMT
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.
P22734
Gene Symbols
Comt
Immunogen
Recombinant Rat COMT protein, Gly63-Ser264 (Accession #P22734)
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Rat
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
C4
Conjugate
Unconjugated
Gene
Comt
Gene Alias
Catechol O-methyltransferase, catecholamine-O-methyltransferase, catechol-O-methyltransferase, catechol-O-methyltransferase 1, catechol-O-methyltransferase isoform, Comt, Comt1, D16Wsu103e, D330014B15Rik, epididymis secretory sperm binding protein Li 98n, HEL-S-98n, OTTHUMP00000197749, OTTHUMP00000197750, testicular tissue protein Li 42
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
24267
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1 κ
Related Products
Description
- Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine
- This O-methylation results in one of the major degradative pathways of the catecholamine transmitters
- In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease
- COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT)
- The differences between S-COMT and MB-COMT reside within the N-termini
- Several transcript variants are formed through the use of alternative translation initiation sites and promoters.