FEMA551160

VNN1 Monoclonal Antibody (C2), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA551160-Each-of-1 In Stock ₹ 16,269.20

FEMA551160 - Each of 1

₹ 16,269.20

In Stock

Quantity

1

Base Price: ₹ 16,269.20

GST (18%): ₹ 2,928.456

Total Price: ₹ 19,197.656

Antigen

VNN1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

O95497, Q9BDJ5

Gene Symbols

VNN1

Immunogen

Recombinant Human VNN1 protein, Gln22-Gly491 (Accession #O95497)

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Porcine

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

C2

Conjugate

Unconjugated

Gene

VNN1

Gene Alias

HDLCQ8, Pantetheinase, pantetheine hydrolase, Tiff66, V-1, vanin 1, Vanin1, vanin-1, vannin 1, vascular non-inflammatory molecule 1, VNN1

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

397246, 8876

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

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Description

  • Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes
  • GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells
  • Vanin-1 is ubiquitously expressed as a pantetheinase enzyme and catalyzes the hydrolysis of pantetheine for vitamin B5 recycling
  • The hydrolytic activity of vanin-1 generates the potent antioxidant cysteamine as a metabolite
  • As a membrane bound pantetheinase, vanin-1 provides the main source of cysteamine under normal physiological conditions
  • In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, where it aids in cell migration.