FEMA551171

ACVR2A Monoclonal Antibody (C1), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA551171-Each-of-1 In Stock ₹ 38,092.00

FEMA551171 - Each of 1

₹ 38,092.00

In Stock

Quantity

1

Base Price: ₹ 38,092.00

GST (18%): ₹ 6,856.56

Total Price: ₹ 44,948.56

Antigen

ACVR2A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

P27037

Gene Symbols

ACVR2A

Immunogen

Recombinant Human ACVR2A protein, Ala20-Pro135 (Accession #P27037)

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Porcine

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

C1

Conjugate

Unconjugated

Gene

ACVR2A

Gene Alias

activin A receptor type 2A, activin A receptor type IIA, activin A receptor, type IIA, activin receptor IIA, activin receptor type IIA, Activin receptor type-2A, Actrii, ActrIIa, ACTR-IIA, ACVR2, Acvr2a, rActR-II, TactrII, type II activin receptor

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

397282, 92

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b κ

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Description

  • Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases
  • ACVR2A is involved in the activin and myostatin signaling pathway
  • (ACVR2A Aliases: ACVR2, ACTRII)
  • These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity
  • Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors
  • Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors
  • Type II receptors are considered to be constitutively active kinases.