FEPA5144252

GAPDH Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEPA5144252-Each-of-1 In Stock ₹ 31,773.00

FEPA5144252 - Each of 1

₹ 31,773.00

In Stock

Quantity

1

Base Price: ₹ 31,773.00

GST (18%): ₹ 5,719.14

Total Price: ₹ 37,492.14

Antigen

GAPDH

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GAPDH

Gene Alias

38 kDa BFA-dependent ADP-ribosylation substrate, aging-associated gene 9 protein, BARS-38, bb02e05, cb350, cb609, CDABP0047, EC 1.2.1.12, epididymis secretory protein Li 278, epididymis secretory sperm binding protein Li 162eP, fb71f08, fk58c09, G3PD, G3PDH, GAPD, GAPD2, gapdh, GAPDH2, GAPDH-2, GAPDHS, Gapds, Gapd-s, glceraldehyde-3-phosphate dehydrogenase, glyceraldehyde 3-phosphate dehydrogenase, glyceraldehyde 3-phosphate dehydrogenase, testis-specific, glyceraldehyde phosphate dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase (G3PDH), glyceraldehyde-3-phosphate dehydrogenase 2, glyceraldehyde-3-phosphate dehydrogenase GAPDH, glyceraldehyde-3-phosphate dehydrogenase like-17 protein, glyceraldehyde-3-phosphate dehydrogenase type 2, glyceraldehyde-3-phosphate dehydrogenase, spermatogenic, glyceraldehyde-3-phosphate dehydrogenase, testis-specific, glyceraldehyde-phosphate-dehydrogenase, glycerine aldehyde 3-phosphate dehydrogenase, HEL-S-162eP, HEL-S-278, HGNC:4141, HSD35, HSD-35, I79_001391, KNC-NDS6, LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase, testis-specific, mg:bb02e05, MGC128279 protein, MGC88685, multifunctional protein, glycolytic enzyme, OK/SW-cl.12, Peptidyl-cysteine S-nitrosylase GAPDH, similar to glyceraldehyde 3-phosphate dehydrogenase, spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2, Spermatogenic glyceraldehyde-3-phosphate dehydrogenase, Unknown (protein for IMAGE:8101613), unnamed protein product, wu:fb33a10, wu:fb71f08, wu:fk58c09, wu:ft80f05, zgc:76908

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100736557, 100767862

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

Applications

ELISA, Western Blot

Concentration

3 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.

P17244

Gene Symbols

GAPDH, GAPDHS

Immunogen

Recombinant Cricetulus griseus Glyceraldehyde-3-phosphate dehydrogenase protein (2-333AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Hamster

Form

Liquid

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Description

  • GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis
  • GAPDH exists as a tetramer of identical 37-kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH
  • Apart from playing a key role in glycolysis, GAPDH is ubiquitously expressed and displays other activities unrelated to its glycolytic function
  • GAPDH is reported to be involved in the processes of DNA replication, DNA repair, nuclear RNA export, membrane fusion and microtubule bundling
  • Studies provide evidence of GAPDH playing an essential part in gene expression observed in apoptosis and as part of the cellular phenotype of age-related neurodegenerative diseases
  • Further, GAPDH is involved in other cellular processes ranging from membrane fusion, and neuronal apoptosis in cancer
  • GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer's disease (AD), and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington's disease
  • Associations between GAPDH, actin and tubulin have also be reported
  • Since GAPDH is expressed at high levels in most tissues, it is useful as protein loading control in Western Blot analysis.