FEPA5144527
IPAB Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEPA5144527-Each-of-1 | In Stock | ₹ 31,773.00 |
FEPA5144527 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,773.00
GST (18%): ₹ 5,719.14
Total Price: ₹ 37,492.14
Antigen
IPAB
Classification
Polyclonal
Conjugate
Unconjugated
Gene
sctE
Gene Alias
ipaB
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
1238055
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Applications
ELISA, Western Blot
Concentration
3.904 mg/mL
Formulation
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Gene Accession No.
P18011
Gene Symbols
sctE
Immunogen
Recombinant Shigella flexneri IPAB protein (1-312aa)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bacteria
Form
Liquid
Related Products
Description
- Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:10545510, PubMed:17367391)
- IpaB/SctE and IpaC/SctB are inserted into the host membrane where they form a pore and allow the translocation of effector proteins into the cytosol of target cells (PubMed:10545510, PubMed:17367391, PubMed:34809452)
- Interaction with IpaD/SctA at needle tips leads to the formation of the MxiH/SctF-IpaD/SctA-IpaB/SctE ternary complex, which is essential for host cell sensing (PubMed:17367391, PubMed:19433542)
- Interaction of IpaB/SctE with host membrane lipids promotes recruitment of IpaC/SctB at the needle tip concomitant with translocon insertion into the host membrane and type III secretion induction (PubMed:19433542).