Carbonic Anhydrase IX Monoclonal Antibody (7C4A5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA548397-Each-of-1 | In Stock | ₹ 43,565.50 |
FERMA548397 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,565.50
GST (18%): ₹ 7,841.79
Total Price: ₹ 51,407.29
Antigen
Carbonic Anhydrase IX
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q16790
Gene Symbols
CA9
Immunogen
Purified recombinant fragment of human CA9 (AA: 37-186) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
7C4A5
Conjugate
Unconjugated
Gene
CA9
Gene Alias
Ca9; CA-9; CAIX; CA-IX; Car9; Carbonate dehydratase IX; carbonic anhydrase 9; Carbonic anhydrase IX; carbonic dehydratase; G250; Membrane antigen MN; membrane antigen MN homolog; MN; MN/CA9; P54 / 58N; P54/58N; pMW1; RCC-associated antigen G250; RCC-associated protein G250; renal cell carcinoma-associated antigen G250
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
768
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions
- It is abundant in all mammalian tissues
- There are many genes that are inducible by hypoxia, via HIF-1 alpha
- CA IX is one of the most inducible genes because of its stability and location within the membrane
- Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux
- The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increased cell death under hypoxia
- Therefore, CA IX has become a reliable histochemical marker of hypoxia.