Caspase 7 Monoclonal Antibody (4D10B2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA548403-Each-of-1 | In Stock | ₹ 43,565.50 |
FERMA548403 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,565.50
GST (18%): ₹ 7,841.79
Total Price: ₹ 51,407.29
Antigen
Caspase 7
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P55210
Gene Symbols
CASP7
Immunogen
Purified recombinant fragment of human CASP-7 (AA: 29-198) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
4D10B2
Conjugate
Unconjugated
Gene
CASP7
Gene Alias
AI314680; Apoptotic protease Mch-3; Casp7; CASP-7; caspase 7; caspase 7, apoptosis-related cysteine peptidase; caspase 7, apoptosis-related cysteine protease; caspase-7; Caspase-7 subunit p11; Caspase-7 subunit p20; CMH-1; cysteine protease LICE2; ICE-IAP3; ICE-LAP3; ICE-like apoptotic protease 3; Lice2; mCASP-7; MCH3; OTTHUMP00000020511; OTTHUMP00000020513; OTTHUMP00000020514; RP11-211N11.6
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
840
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- Caspase 7 is part of a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies
- Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens
- The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that μgtimately lead to cell death
- Caspase 7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C
- elegans cell death protein CED-3
- Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms
- Caspase-7 activity can be directly inhibited by XIAP expression
- Alternative splicing results in four transcript variants, encoding three distinct isoforms of Caspase 7
- Diseases associated with CASP7 include Type 1 Diabetes Mellitus 17 and Aleutian Mink Disease.