FERMA548412

SR-BI Monoclonal Antibody (5E9H10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA548412-Each-of-1 In Stock ₹ 43,565.50

FERMA548412 - Each of 1

₹ 43,565.50

In Stock

Quantity

1

Base Price: ₹ 43,565.50

GST (18%): ₹ 7,841.79

Total Price: ₹ 51,407.29

Antigen

SR-BI

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q8WTV0

Gene Symbols

SCARB1

Immunogen

Purified recombinant fragment of human SCARB1 (AA: Extra(33-232)) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

5E9H10

Conjugate

Unconjugated

Gene

SCARB1

Gene Alias

AI120173; CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen (collagen type I receptor, thrombospondin receptor-like 1); CD36 antigen-like 1; Cd36l1; CD36-related class B scavenger receptor haSR-BI; CLA1; Cla-1; Collagen type I receptor, thrombospondin receptor-like 1; D5Ertd460e; haSR-bI; HDL QTL 1; Hdlq1; HDLQTL6; high density lipoprotein receptor; Hlb398; mSR-BI; Scarb1; scavanger receptor class B type 1; scavenger receptor b1; scavenger receptor class B member 1; scavenger receptor class B type I; scavenger receptor class B type II; scavenger receptor class B type III; scavenger receptor class B, member 1; scavenger receptor class B1; SRB1; SR-B1; SRBI; SR-BI; SR-BII

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

949

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2a

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Description

  • High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis
  • The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester
  • SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism
  • In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.