FGFR3 Monoclonal Antibody (1E3F9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA548457-Each-of-1 | In Stock | ₹ 43,565.50 |
FERMA548457 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,565.50
GST (18%): ₹ 7,841.79
Total Price: ₹ 51,407.29
Antigen
FGFR3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P22607
Gene Symbols
FGFR3
Immunogen
Purified recombinant fragment of human FGFR3 (AA: 529-694) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
1E3F9
Conjugate
Unconjugated
Gene
FGFR3
Gene Alias
ACH; CD333; CEK2; FGFR3; FGFR-3; FGFR3deltaTM; Fibroblast growth factor receptor 3; fibroblast growth factor receptor 3 variant 4; Flg-2; FR3; HBGFR; heparin-binding growth factor receptor; HSFGFR3EX; hydroxyaryl-protein kinase; JTK4; Mfr3; sam3; tyrosine kinase JTK4
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
2261
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG2a
Related Products
Description
- FGFR3 is a member of the FGFR family of receptor tyrosine kinases
- This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury
- The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy
- FGFR family members differ from one another in their ligand affinities and tissue distribution
- A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain
- The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, μgtimately influencing mitogenesis and differentiation
- This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance
- Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia
- Three alternatively spliced transcript variants that encode different protein isoforms have been described.