FERMA548516

Integrin alpha V (CD51) Monoclonal Antibody (3H1A5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA548516-Each-of-1 In Stock ₹ 43,565.50

FERMA548516 - Each of 1

₹ 43,565.50

In Stock

Quantity

1

Base Price: ₹ 43,565.50

GST (18%): ₹ 7,841.79

Total Price: ₹ 51,407.29

Antigen

Integrin alpha V (CD51)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P06756

Gene Symbols

ITGAV

Immunogen

Purified recombinant fragment of human CD51 (AA: extra 31-189) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Western Blot

Clone

3H1A5

Conjugate

Unconjugated

Gene

ITGAV

Gene Alias

1110004F14Rik; 2610028E01Rik; alpha v integrin; antigen identified by monoclonal antibody L230; Cd51; CD61; D430040G12Rik; Dnmt3l-ps1 pseudogene; GP3A; GPIIIa; integrin alpha V; integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; integrin subunit alpha V; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); ITGAV; ITGB3; MSK8; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); vitronectin receptor subunit alpha; VNR; VNRA; VTNR

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3685

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • ITAGV encodes integrin alpha chain V
  • Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain
  • The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins
  • Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR)
  • In addition to adhesion, many integrins are known to facilitate signal transduction
  • The ITGB3 protein product is the integrin beta chain beta 3
  • Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain
  • A given chain may combine with multiple partners resulting in different integrins
  • Integrin beta 3 is found along with the alpha IIb chain in platelets
  • Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.