FERMA548534

CD223 (LAG-3) Monoclonal Antibody (4H6A3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA548534-Each-of-1 In Stock ₹ 43,565.50

FERMA548534 - Each of 1

₹ 43,565.50

In Stock

Quantity

1

Base Price: ₹ 43,565.50

GST (18%): ₹ 7,841.79

Total Price: ₹ 51,407.29

Antigen

CD223 (LAG-3)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P18627

Gene Symbols

LAG3

Immunogen

Purified recombinant fragment of human CD223 (AA: extra 66-199) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Western Blot

Clone

4H6A3

Conjugate

Unconjugated

Gene

LAG3

Gene Alias

Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3902

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
  • LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
  • Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
  • CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
  • Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).