NOTCH3 Monoclonal Antibody (2E4D11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA548560-Each-of-1 | In Stock | ₹ 43,565.50 |
FERMA548560 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,565.50
GST (18%): ₹ 7,841.79
Total Price: ₹ 51,407.29
Antigen
NOTCH3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q9UM47
Gene Symbols
Notch3
Immunogen
Purified recombinant fragment of human Notch3 (AA: 47-156) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
2E4D11
Conjugate
Unconjugated
Gene
Notch3
Gene Alias
AW229011; CADASIL; CADASIL1; CASIL; hpbk; IMF2; LMNS; N3; Neurogenic locus notch homolog protein 3; notch 3; Notch 3 extracellular truncation; Notch 3 intracellular domain; Notch gene homolog 3; Notch homolog 3; NOTCH3
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
4854
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG2b
Related Products
Description
- NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch
- In Drosophilia, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development
- Homologues of the notch-ligands have also been identified in human
- NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination
- Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).