KMT2D Monoclonal Antibody (1D10F6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA548640-Each-of-1 | In Stock | ₹ 43,565.50 |
FERMA548640 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,565.50
GST (18%): ₹ 7,841.79
Total Price: ₹ 51,407.29
Antigen
KMT2D
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O14686
Gene Symbols
KMT2D
Immunogen
Purified recombinant fragment of human KMT2D (AA: 445-599) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
1D10F6
Conjugate
Unconjugated
Gene
KMT2D
Gene Alias
AAD10; ALL1-related protein; ALR; CAGL114; Histone-lysine N-methyltransferase 2D; histone-lysine N-methyltransferase MLL2; KABUK1; Kabuki make-up syndrome; Kabuki mental retardation syndrome; KMS; KMT2D; lysine (K)-specific methyltransferase 2D; lysine methyltransferase 2D; lysine N-methyltransferase 2D; MLL2; MLL4; myeloid/lymphoid or mixed-lineage leukemia 2; Myeloid/lymphoid or mixed-lineage leukemia protein 2; TNRC21; trinucleotide repeat containing 21
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
8085
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG2b
Related Products
Description
- KMT2D is a histone methyltransferase that methylates Lys-4 of histone H3 (H3K4me)
- H3K4me represents a specific tag for epigenetic transcriptional activation
- KMT2D acts as a coactivator for estrogen receptors by being recruited by ESR1 and activating transcription
- KMT2D is involved in chromatin organization, chormatin silencig, oocyte growth, oogenesis, and a positive regulation of cell proliferation
- Mutations in the KMT2D gene cause Kabuki syndrome (KABUK1) which results in congential mental retardation syndrome.