KIM-1 Monoclonal Antibody (3A12E10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA548727-Each-of-1 | In Stock | ₹ 43,565.50 |
FERMA548727 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,565.50
GST (18%): ₹ 7,841.79
Total Price: ₹ 51,407.29
Antigen
KIM-1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q96D42
Gene Symbols
Havcr1
Immunogen
Purified recombinant fragment of human HAVCR1 (AA: 70-290) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Clone
3A12E10
Conjugate
Unconjugated
Gene
Havcr1
Gene Alias
AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
26762
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail
- The endogenous ligand for CD365 is Tim-4
- In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus
- The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes
- Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity
- CD365 has also been implicated in the T cell co-stimulation
- CD365 is primarily expressed in epithelial cells
- It is also highly expressed in A549, 769-P and Caco-2 and cell lines
- CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.