CD40 Monoclonal Antibody (5C3), NovaFluor™ Yellow 610, eBioscience™, Invitrogen™
Manufacturer: LIFE TECHNOLOGIES
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | H027T03Y03A-Each-of-1 | In Stock | ₹ 35,155.00 |
H027T03Y03A - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,155.00
GST (18%): ₹ 6,327.90
Total Price: ₹ 41,482.90
Antigen
CD40
Classification
Monoclonal
Concentration
0.6 μg/Test
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P25942
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Format
Liquid
Applications
Flow Cytometry
Clone
5C3
Conjugate
NovaFluor Yellow 610
Gene
CD40
Gene Alias
AI326936, B cell surface antigen CD40, B cell-associated molecule, B-cell surface antigen CD40, Bp50, CD antigen CD40, Cd40, CD40 antigen, CD40 antigen (TNF receptor superfamily member 5), CD40 antigen, TNF receptor superfamily member 5, CD40 molecule, CD40 molecule, TNF receptor superfamily member 5, CD40L receptor, CDw40, GP39, HIGM1, I79_006806, IGM, IMD3, Immunoglobulin M, ImmunoglobulinM, membrane protein CD40, MGC9013, p50, receptor for ligand CD154, sCD40, soluble CD40, T-BAM, T-cell differentiation antigen, Tnfrsf5, TRAP, tumor necrosis factor receptor superfamily member 5, tumor necrosis factor receptor superfamily, member 5
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
958
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Isotype
IgG1 κ
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Description
- The 5C3 mAb reacts with human CD40, a 45-50 kDa type I transmembrane glycoprotein
- CD40 is a member of the TNFR family and is expressed by B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells
- CD40 regulates B cell development and maturation by inducing Ig isotype-switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation
- Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation
- 5C3 is reported to be used for activation of B cells in in vitro functional assays
- The 5C3 antibody has been reported for use in flow cytometric analysis
- The 5C3 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 5 uL (0.6 ug) per test
- A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 uL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- NovaFluor dyes are not compatible with DNA intercalating viability dyes
- Invitrogen LIVE/DEAD Fixable Dead Cell stains are recommended for use with NovaFluor dyes
- Each NovaFluor conjugate or kit is shipped with CellBlox Blocking Buffer Excitation: 552 nm; Emission: 612 nm; Laser: 561 nm (Yellow) Laser CD40 Monoclonal antibody specifically detects CD40 in Human samples
- It is validated for Flow Cytometry