Cytokeratin 18 Monoclonal Antibody (RGE53), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA106326-Each-of-1 | In Stock | ₹ 53,044.00 |
MA106326 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,044.00
GST (18%): ₹ 9,547.92
Total Price: ₹ 62,591.92
Antigen
Cytokeratin 18
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P05783, P05784, Q5BJY9, Q7ZTS4
Gene Symbols
KRT18, LOC100008885
Immunogen
Cytoskeletal preparation of HeLa cells
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Chicken, Hamster, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone
RGE53
Conjugate
Unconjugated
Gene
KRT18
Gene Alias
cb83; Cell proliferation-inducing gene 46 protein; CK 18; CK18; CK-18; CYK18; cytokeratin 18; cytokeratin endo B; cytokeratin type -1; DAPK-1; Cytokeratin18; cytokeratin-18; dapk1; dorsal aorta proneprin kinesin-1; DreK18; Endo B; I79_023185; K 18; K18; keratin 18; keratin 18, type I; keratin 18a, tandem duplicate 1; keratin complex 1, acidic, gene 18; keratin D; Keratin, type I cytoskeletal 18; Keratin18; keratin-18; Kerd; KRT 18; Krt1-18; KRT18; krt18 {ECO:0000250; krt18a.1; LOC100008885; PIG46; sb:cb83; type I cytoskeletal 18; UniProtKB:P05783}; wu:fa13f02; wu:fb36b04
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
100008885, 100126286, 100354174, 100759201, 101749333, 16668, 294853, 352912, 3875, 477601
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA1-06326 detects cytokeratin 18 in human, mouse, rat, hamster, rabbit, chicken, canine, zebrafish and swine samples
- MA1-06326 has sucessfully been used in Western blotting, immunocytochemistry, flow cytometry, and immunohistochemistry
- The MA1-06326 immunogen is a cytoskeletal preparation from cells
- Store at 4oC or in small aliquots at -20oC
- Cytokeratin 18 (Keratin 18, KRT18, type I cytoskeletal 18) belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8
- Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18
- Further, cytokeratin 18 is found primarily in non-squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas, but not in squamous cell carcinomas
- Hepatocellular carcinomas express only cytokeratins 8 and 18
- Mutations in the cytokeratin 18 gene have been linked to cryptogenic cirrhosis
- Two transcript variants encoding the same protein have been found for the cytokeratin 18 gene
- Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies
- The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.