MA125130

GP130 (soluble) Monoclonal Antibody (B-T2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA125130-Each-of-1 In Stock ₹ 49,884.50

MA125130 - Each of 1

₹ 49,884.50

In Stock

Quantity

1

Base Price: ₹ 49,884.50

GST (18%): ₹ 8,979.21

Total Price: ₹ 58,863.71

Antigen

GP130 (soluble)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P40189

Gene Symbols

IL6ST

Immunogen

Natural, soluble human CD130.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Flow Cytometry

Clone

B-T2

Conjugate

Unconjugated

Gene

IL6ST

Gene Alias

5133400A03Rik; AA389424; Ac1055; BB405851; CD130; CD130 antigen; CDW130; D13Ertd699e; EGK_16499; Gp130; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; gp130, oncostatin M receptor; GP130-RAPS; IL-6; IL-6 receptor subunit beta; IL-6R subunit beta; IL-6RB; IL-6R-beta; IL6R-beta; IL6ST; interleukin 6 signal transducer; interleukin 6 signal transducer (gp130, oncostatin M receptor); interleukin 6 signal transducer receptor; interleukin receptor beta chain; interleukin-6 receptor subunit beta; Interleukin-6 signal transducer; interleukin-6 signal transducer receptor; membrane glycoprotein; membrane glycoprotein 130; membrane glycoprotein gp130; oncostatin-M receptor subunit alpha

Host Species

Mouse

Purification Method

Ion-exchange chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3572

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA1-25130 detects CD130 (gp130) from human samples
  • The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM)
  • This protein functions as a part of the cytokine receptor complex
  • The activation of this protein is dependent upon the binding of cytokines to their receptors
  • vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein
  • Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis
  • Alternatively spliced transcript variants encoding distinct isoforms have been described.