MABC563MI

MilliporeSigma™ Mouse anti-Kallikrein 2/KLK2, Clone: 4F2.3,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABC563MI-Each-of-1 In Stock ₹ 44,393.20

MABC563MI - Each of 1

₹ 44,393.20

In Stock

Quantity

1

Base Price: ₹ 44,393.20

GST (18%): ₹ 7,990.776

Total Price: ₹ 52,383.976

Antigen

Kallikrein 2/KLK2

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

KLK2

Immunogen

GST-tagged recombinant protein corresponding to human Kallikrein 2/KLK2.

Quantity

100 μg

Research Discipline

Apoptosis, Cancer

Gene ID (Entrez)

NP_005542

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG1 κ

Applications

Immunohistochemistry, Western Blot

Clone

4F2.3

Gene Accession No.

P20151

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects Kallikrein 2/KLK2 clone: 4F2.3 in Human samples, and it is validated for Immunohistochemistry, Western Blotting Kallikrein-2, also known as Glandular kallikrein-1 (hGK-1) or Tissue kallikrein-2, is encoded by the KLK2 gene
  • Kallikrein-2 is a serine protease produced by secretory epithelial cells in the prostate
  • Kallikrein-2 cleaves Met-Lys and Arg-Ser amide linkages in kininogen to release Lys-bradykinin
  • It is also known to activate the proforms of prostate-specific antigen (PSA) and urokinase type plasminogen activator (uPA), as well as inactivate plasminogen activator inhibitor-1 (PAI-1)
  • both PSA and Kallikrein-2 are used as prostate cancer markers.