MABE1126MI

DNA G-quadruplex (G4) Mouse anti-All, Clone: 1H6, MilliporeSigma™

Manufacturer: MilliporeSigma

Select a Size

Pack Size SKU Availability Price
Each of 1 MABE1126MI-Each-of-1 In Stock ₹ 47,205.60

MABE1126MI - Each of 1

₹ 47,205.60

In Stock

Quantity

1

Base Price: ₹ 47,205.60

GST (18%): ₹ 8,497.008

Total Price: ₹ 55,702.608

Antigen

DNA G-quadruplex (G4)

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

All species

Form

Purified

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), ELISA, Flow Cytometry

Clone

1H6

Conjugate

Unconjugated

Immunogen

KLH-conjugated G-quadruplex DNA derived from oligonucleotides with telomeric repeats.

Quantity

100 μg

Research Discipline

Epigenetics and Nuclear Function

Test Specificity

Clone 1H6 binds both tetramolecular and unimolecular (intramolecular) DNA G-quadruplex (G4) structures without sequence specificity, while exhibiting significantly lower affinity toward tetramolecular RNA structure or a triplex DNA structure, and little to no affinity toward either non-G4 ssDNA or ddDNA. However, clone 1H6 does not seem to bind the [AGGG(TTAGGG)3] unimolecular G4 structure, indicating a broad selectivity toward many, but not all, DNA G4 structures (Henderson, A., et al. (2014). Nucleic Acids Res. 42(2):860-869).

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG2b κ

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Description

  • This Anti-DNA G-quadruplex (G4) Antibody, clone 1H6 is validated for use in Immunocytochemistry, Immunohistochemistry (Paraffin), ELISA and Flow Cytometry for the detection of DNA G-quadruplex .