MABF1493MI
MilliporeSigma™ anti- CD161 (NK1.1) PerCP-Cy5.5, Clone: PK136,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF1493MI-Each-of-1 | In Stock | ₹ 16,846.81 |
MABF1493MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,846.81
GST (18%): ₹ 3,032.426
Total Price: ₹ 19,879.236
Antigen
CD161 (NK1.1)
Classification
Monoclonal
Conjugate
PerCP-Cyanine5.5
Gene Accession No.
P27812
Host Species
Mouse
Purification Method
Purified by size-exclusion chromatography
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
PK136
Formulation
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols
Klrb1b, Ly55b, Nkrp1b
Immunogen
Proprietary immunogen
Quantity
25 μg
Research Discipline
Inflammation, Immunology
Target Species
Mouse
Form
Purified
Related Products
Description
- Specifically detects CD161 (NK1.1) Clone: PK136 in Mouse samples, and it is validated for Flow Cytometry The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family
- NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells
- NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129)
- Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al
- 2012
- Endocrinology
- 10: 1247).The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB
- The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al
- 2006
- J
- Immunol
- 176: 7511-7524).