MABF1512MI
MilliporeSigma™ anti-CD127 (IL-7Ra) Violer Fluor 450, Clone: A7R34,
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF1512MI-Each-of-1 | In Stock | ₹ 50,816.33 |
MABF1512MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,816.33
GST (18%): ₹ 9,146.939
Total Price: ₹ 59,963.269
Antigen
CD127 (IL-7Ra)
Classification
Monoclonal
Conjugate
Violet Fluor 450 (V450)
Gene Accession No.
P16872
Host Species
Rat
Purification Method
Purified by size-exclusion chromatography
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Applications
Flow Cytometry
Clone
A7R34
Formulation
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols
Il7r
Immunogen
Proprietary immunogen
Quantity
100 μg
Research Discipline
Inflammation, Immunology
Target Species
Mouse
Form
Purified
Related Products
Description
- Specifically detects CD127 (IL-7Ra) Clone: A7R34 in Mouse samples, and it is validated for Flow Cytometry The A7R34 antibody is specific for mouse CD127, a 60-90kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha
- CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132)
- This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis
- A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.The A7R34 antibody may be used as a phenotypic marker for CD127 on immature B cells, on subsets of thymocytes which are double negative (CD4-CD8- ) or single positive (CD4+ or CD8+), and at low levels on mature, peripheral T cells
- CD127 is a key marker, when used in combination with CD4 and CD25, to distinguish Treg and effector/memory Treg populations known as T(REM).